Last update June 28, 2022
Limited compatibility
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 100 | % |
Molecular weight | 176 | daltons |
Protein Binding | 50 | % |
Tmax | 4 | hours |
T½ | 12 | hours |
Write us at elactancia.org@gmail.com
e-lactancia is a resource recommended by La Liga de la Leche, España of Spain
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Pemoline is a central nervous system (CNS) stimulant with actions similar to those of dexamfetamine. It has been used to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy. It has been withdrawn from the market in many countries due to its hepatotoxicity. (Formulary Watch 2005, Safer 2001)
Since the last update we have not found published data on its excretion in breastmilk.
Its pharmacokinetic data (low molecular weight and low percentage of plasma protein binding) makes it likely that significant amounts will pass into breast milk.