Last update Jan. 12, 2023
Very Low Risk
We do not have alternatives for Pancreatic Enzymes since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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e-lactancia is a resource recommended by Asociación Pro Lactancia Materna (APROLAM) of Mexico
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Pancreatic enzymes (such as pancreatin or pancrelipase) are preparations of mammalian (pig, ox) pancreas that contain enzymes that have protease, lipase, and amylase activity. They hydrolyze fats into glycerol and fatty acids, break down proteins into peptides and proteoses, and convert starch into dextrins and sugars. They are administered orally to treat malabsorption associated with exocrine pancreatic deficiencies, such as pancreatitis and cystic fibrosis.
At latest update no published data on excretion into breast milk was found.
Pancreatic enzymes act locally in the gastrointestinal tract and are not absorbed in significant amounts. (Vivus 2020, AEMPS 2012)
Its high molecular weight and insignificant intestinal absorption make its passage into breast milk very unlikely.
A low oral bioavailability hinders the passage into infant plasma from ingested breast milk.
It is a medication used in children and young infants.
The manufacturer considers this medicine compatible with breastfeeding. (Vivus 2020, AEMPS 2012)