Last update June 1, 2020


Likely Compatibility

Fairly safe. Mild or unlikely adverse effects. Compatible under certain circumstances. Follow-up recommended. Read Commentary.

Hepatitis C virus NS5A protein inhibitor.
Used in combination with glecaprevir in the treatment of chronic hepatitis C virus infection.
Oral administration in a daily dose for 8 to 16 weeks.

Since the last update we have not found any published data on its excretion in breast milk.

Its pharmacokinetic characteristics (lelevated molecular weight and very high plasma protein binding: EMA 2019, AEMPS 2019, Smolders 2019) make it very unlikely its excretion into breast milk in significant amounts

Possible side effects are rare and mild.

See below the information of these related products:

  • Glecaprevir (Fairly safe. Mild or unlikely adverse effects. Compatible under certain circumstances. Follow-up recommended. Read Commentary.)
  • Maternal Hepatitis C Infection (Safe substance and/or breastfeeding is the best option.)


We do not have alternatives for 哌仑他韦.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.


哌仑他韦 belongs to this group or family:


Main tradenames from several countries containing 哌仑他韦 in its composition:

  • Maviret™. Contains other elements than 哌仑他韦 in its composition
  • Mavyret™. Contains other elements than 哌仑他韦 in its composition


Variable Value Unit
Molecular weight 1.113 daltons
Protein Binding 100 %
Tmax 5 hours
13 - 29 hours


  1. EMA. Maviret (Glecaprevir + Pibrentasvir) Drug Summary 2019 Full text (in our servers)
  2. Smolders EJ, Jansen AME, Ter Horst PGJ, Rockstroh J, Back DJ, Burger DM. Viral Hepatitis C Therapy: Pharmacokinetic and Pharmacodynamic Considerations: A 2019 Update. Clin Pharmacokinet. 2019 Oct;58(10):1237-1263. Abstract
  3. AEMPS. Maviret (Glecaprevir + Pibrentasvir) Ficha técnica. 2019 Full text (in our servers)

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