Last update April 24, 2025

Oxolamine Citrate; Oxolamine Phosphate

Limited compatibility

Unsafe. Moderate/severe adverse effects. Compatible under certain circumstances. Follow-up recommended. Use safer alternative or discontinue breastfeeding from 5 to 7 T ½ . Read Commentary.

Non-opioid antitussive for which there are very few bibliographic references.

At the date of the last update, there are no published data on its excretion in breast milk.

There are no known pharmacokinetic data to estimate possible excretion in breast milk.

It has caused adverse reactions in children. (Meyboom 1991, McEwen 1989)

Pending further published data on this drug in relation to breastfeeding, safer known alternatives may be preferable, especially during the neonatal period and in case of prematurity.

Alternatives

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Oxolamine Citrate; Oxolamine Phosphate is also known as Oxolamine.


Oxolamine Citrate; Oxolamine Phosphate in other languages or writings:

Group

Oxolamine Citrate; Oxolamine Phosphate belongs to this group or family:

Tradenames

Main tradenames from several countries containing Oxolamine Citrate; Oxolamine Phosphate in its composition:

Pharmacokinetics

Variable Value Unit
Molecular weight 245 daltons
3 - 4 hours

References

  1. Meyboom RH. Adverse reaction to drugs in children, experiences with "spontaneous monitoring" in The Netherlands. Bratisl Lek Listy. 1991 Abstract
  2. McEwen J, Meyboom RH, Thijs I. Hallucinations in children caused by oxolamine citrate. Med J Aust. 1989 Abstract

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