Last update Oct. 9, 2016

Non-Hormonal Vaginal Lubricant

Very Low Risk

Safe. Compatible. Minimal risk for breastfeeding and infant.

Non-hormonal vaginal lubricants are basically compounded by water or oil, either natural or mineral, or silicone. They may contain water, vegetable oils, glycerin, silicone, citric acid, polyethylene glycol (PEG), polypropylene glycol (PPG) and other products. Make sure that they are licensed and devoid of non-toxic products, since their vaginal absorption may be significant with excretion to mother's blood without any previous metabolization.

Non-hormonal lubricants (creams, gels or eggs) intended to treat a possible dryness of vagina due to hypoestrogenism during lactation, diabetes, after treatment for breast or gynecologic cancer are preferred than the use of topical estrogen-containing products, since a prolonged use might theoretically decrease the breastmilk production if highly absorbed.

Lubricants, in order to avoid any harm to the vaginal mucosa and the health of women, must meet some requirements, among which are included: ideal osmolarity should be less of 380 mOsm / Kg (by no means over 1,200 mOsm / Kg: less than 9% of glycols), pH 4.5, should neither contain spermicides (nonoxynol-9) ,nor drugs (eg anesthetics), nor herbal products, nor polyquaternary compounds, nor products that may alter the wholeness of condoms (WHO / UNFPA / FHI 2012).

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Non-Hormonal Vaginal Lubricant is also known as


Non-Hormonal Vaginal Lubricant belongs to this group or family:


Main tradenames from several countries containing Non-Hormonal Vaginal Lubricant in its composition:


  1. Hickey M, Marino JL, Braat S, Wong S. A randomized, double-blind, crossover trial comparing a silicone- versus water-based lubricant for sexual discomfort after breast cancer. Breast Cancer Res Treat. 2016 Abstract
  2. Huffman LB, Hartenbach EM, Carter J, Rash JK, Kushner DM. Maintaining sexual health throughout gynecologic cancer survivorship: A comprehensive review and clinical guide. Gynecol Oncol. 2016 Abstract
  3. Herbenick D, Reece M, Schick V, Sanders SA, Fortenberry JD. Women's use and perceptions of commercial lubricants: prevalence and characteristics in a nationally representative sample of American adults. J Sex Med. 2014 Abstract
  4. Nicole W. A question for women's health: chemicals in feminine hygiene products and personal lubricants. Environ Health Perspect. 2014 Abstract
  5. Cunha AR, Machado RM, Palmeira-de-Oliveira A, Martinez-de-Oliveira J, das Neves J, Palmeira-de-Oliveira R. Characterization of commercially available vaginal lubricants: a safety perspective. Pharmaceutics. 2014 Abstract
  6. Fashemi B, Delaney ML, Onderdonk AB, Fichorova RN. Effects of feminine hygiene products on the vaginal mucosal biome. Microb Ecol Health Dis. 2013 Abstract
  7. Brown JM, Hess KL, Brown S, Murphy C, Waldman AL, Hezareh M. Intravaginal practices and risk of bacterial vaginosis and candidiasis infection among a cohort of women in the United States. Obstet Gynecol. 2013 Abstract
  8. WHO/UNFPA/FHI360. Use and procurement of additional lubricants for male and female condoms. Advisory note. 2012 Full text (link to original source) Full text (in our servers)
  9. Wolf LK. Studies raise questions about safety of personal lubricants. Chem Eng News. 2012;90(50):46–47 2012 Full text (link to original source) Full text (in our servers)
  10. Gupta S, Gabrani R, Ali J, Dang S. Exploring novel approaches to vaginal drug delivery. Recent Pat Drug Deliv Formul. 2011 Abstract
  11. Hussain A, Ahsan F. The vagina as a route for systemic drug delivery. J Control Release. 2005 Abstract
  12. Tourgeman DE, Slater CC, Stanczyk FZ, Paulson RJ. Endocrine and clinical effects of micronized estradiol administered vaginally or orally. Fertil Steril. 2001 Abstract
  13. Tourgeman DE, Gentzchein E, Stanczyk FZ, Paulson RJ. Serum and tissue hormone levels of vaginally and orally administered estradiol. Am J Obstet Gynecol. 1999 Abstract

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