Last update Dec. 25, 2021
Very Low Risk
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Nitrofurantoin in other languages or writings:
Nitrofurantoin belongs to this group or family:
Main tradenames from several countries containing Nitrofurantoin in its composition:
|Oral Bioavail.||40 - 90||%|
|Protein Binding||60 - 90||%|
|Tmax||1.5 - 5||hours|
|T½||0.3 - 1||hours|
|M/P ratio||0.3 - 6||-|
|Theoretical Dose||0.075 - 0.41||mg/Kg/d|
|Relative Dose||1 - 6||%|
|Ped.Relat.Dose||1 - 6||%|
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e-lactancia is a resource recommended by Asociación Pro Lactancia Materna (APROLAM) of Mexico
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
It is an antibacterial used in the treatment and prophylaxis of uncomplicated lower urinary-tract infections. Oral administration four times daily.
Excretion into breast milk is clinically non-significant or undetectable (Gerk 2001, Pons 1990, Varsano 1973, Hosbach 1967) with no side-effects observed among breastfed infants from treated mothers except rare cases of diarrhea.(Ito 1993)
Do not use in premature infants, while the infant is younger of two weeks of age or suffers hyperbilirubinemia or G-6-P dehydrogenase (G6PD) deficiency to avoid likelihood of hemolysis. (Zao 2014, WHO 2002, AAP 2001, Mactal 2001).
Be aware the possibility of developing diarrhea due to bacterial flora imbalance.
Expert authors consider the use of nitrofurantoin to be safe during breastfeeding (Hale, LactMed, Briggs 2015, Schaefer2015, Zao 2014, Amir 2011, Mactal 2001). American Academy of Pediatrics: medication usually compatible with breastfeeding (AAP 2001). List of WHO essential medicines: compatible with breastfeeding. (WHO / UNICEF 2002)