Last update Jan. 12, 2024

Methylcellulose

Compatible

Safe substance and/or breastfeeding is the best option.

Product used as a laxative, as a vehicle in eye drops (artificial tears), and as an excipient, emulsifier, thickener and stabilizer in the pharmaceutical and food industries. It is obtained by processing the pulp of various plants, both herbaceous and trees. 

At the time of last update we found no published data on its excretion in breast milk.

The molecular weight varies according to the type of plant from which it is obtained; most commonly it exceeds 100,000 daltons.

Its pharmacokinetic data (no oral bioavailability = no intestinal absorption and a very high molecular weight) make it impossible to pass into breast milk.

Alternatives

We do not have alternatives for Methylcellulose since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Methylcellulose in other languages or writings:

Tradenames

Main tradenames from several countries containing Methylcellulose in its composition:

  • Celevac
  • Citrucel
  • Exxon (India)™. Contains other elements than Methylcellulose in its composition
  • Fibropil (India)™. Contains other elements than Methylcellulose in its composition
  • Kolantyl™. Contains other elements than Methylcellulose in its composition
  • Lacrimart
  • Lubri-Mucal™. Contains other elements than Methylcellulose in its composition
  • Merankol Pastiglie™. Contains other elements than Methylcellulose in its composition
  • Muciplazma
  • N-Zolin (India)™. Contains other elements than Methylcellulose in its composition
  • NCZ (India)™. Contains other elements than Methylcellulose in its composition
  • Nefacool (India)™. Contains other elements than Methylcellulose in its composition
  • Ofet-H (India)™. Contains other elements than Methylcellulose in its composition
  • Vaselina Emulsionada™. Contains other elements than Methylcellulose in its composition

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 0 %
Molecular weight 22.000 - 244.000 daltons
0.07 hours

References

  1. AEMPS. Metilcelulosa. Ficha técnica. 2013 Full text (in our servers)
  2. Frizelle F, Barclay M. Constipation in adults. Clin Evid (Online). 2007 Abstract Full text (link to original source) Full text (in our servers)
  3. Johanson JF. Review of the treatment options for chronic constipation. MedGenMed. 2007 Abstract Full text (link to original source) Full text (in our servers)

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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America

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