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1st generation antihistamine, derived from ethylenediamine, with important sedative and antimuscarinic effects. It is used orally for the symptomatic treatment of cough and common cold and as hypnotic in insomnia. As a skin cream it is used for insect bites and pruritus.
At the time of the last update, we did not find published data on its excretion in breast milk.
Drug with little bibliographic support and marketed in very few countries. Component of many “over-the-counter” drugs in polyassociation with expectorants, bronchodilators, antitussives, etc. It is advisable to avoid drug associations, especially during lactation.
It has an antiprolactin effect that could inhibit lactation in the first weeks after delivery.
Although its occasional and moderate use during lactation is probably safe, until more published data on this drug in relation to lactation is known, safer alternatives are preferable.
Topical use as a dermatological preparation is safe during lactation. Do not apply to the breast.
Monitor drowsiness and adequate feeding of the infant.
Due to its sedative effect, bed sharing with the infant is not recommended if this drug is being taken. (UNICEF 2018, 2017, 2017, 2014, 2014, 2013 and 2006, Landa 2012, ABM 2008)