Last update Dec. 18, 2013

Meclofenamic Acid

Low Risk

Possibly safe. Probably compatible. Mild risk possible. Follow up recommended. Read the Comment.

On latest update no published data about breastfeeding were found

Its high plasma protein binding makes excretion into breast milk unlikely

Until more information on this drug concerning breastfeeding is available, a safer alternative is preferred.


  • Ibuprofen ( Safe. Compatible. Minimal risk for breastfeeding and infant.)
  • Paracetamol ( Safe. Compatible. Minimal risk for breastfeeding and infant.)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Meclofenamic Acid is also known as


Main tradenames from several countries containing Meclofenamic Acid in its composition:


Variable Value Unit
Oral Bioavail. 100 %
Molecular weight 296 daltons
Protein Binding > 99 %
Tmax 0.5 - 2 hours
2 - 4 hours


  1. Conroy MC, Randinitis EJ, Turner JL. Pharmacology, pharmacokinetics, and therapeutic use of meclofenamate sodium. Clin J Pain. 1991 Abstract
  2. Koup JR, Tucker E, Thomas DJ, Kinkel AW, Sedman AJ, Dyer R, Sharoky M. A single and multiple dose pharmacokinetic and metabolism study of meclofenamate sodium. Biopharm Drug Dispos. 1990 Abstract

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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2006 of United States of America

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