Last update Nov. 27, 2016

Magnesium Oxide

Compatible

Safe substance and/or breastfeeding is the best option.

Ingested Magnesium does not concentrate into breast milk.

Naturally occurring, the mean Magnesium concentration in the milk is 31 mg/L (range 15 – 64 mg/L) and not affected by the ingestion of Magnesium.

Because of a low oral bioavailability the pass from the breast milk toward the infant's plasma is hampered, except in premature and newborn infants who may exhibit a higher intestinal absorption due to an increased permeability.

Avoid chronic or excessive use.

WHO Model List of Essential Medicines 2002: Magnesium oxide is compatible with breastfeeding.

Alternatives

We do not have alternatives for Magnesium Oxide since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

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José María Paricio, founder of e-lactancia.
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Groups

Magnesium Oxide belongs to these groups or families:

Tradenames

Main tradenames from several countries containing Magnesium Oxide in its composition:

List of 9 tradenames
  • 102 Plus™. Contains other elements than Magnesium Oxide in its composition
  • Active Calcium™. Contains other elements than Magnesium Oxide in its composition
  • Andino Diure™. Contains other elements than Magnesium Oxide in its composition
  • CitraFleet™. Contains other elements than Magnesium Oxide in its composition
  • Elevit™. Contains other elements than Magnesium Oxide in its composition
  • Eupeptina™. Contains other elements than Magnesium Oxide in its composition
  • Magnesio Vital™. Contains other elements than Magnesium Oxide in its composition
  • Multibionta Complex™. Contains other elements than Magnesium Oxide in its composition
  • Oblax A-1-1™. Contains other elements than Magnesium Oxide in its composition

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 10 - 30 %
Molecular weight 40 daltons

References

  1. Hale TW. Medications & Mothers' Milk. 1991- . Springer Publishing Company. Available from https://www.halesmeds.com Consulted on April 10, 2024 Full text (link to original source)
  2. MedlinePlus. Magnesio en la dieta. Enciclopedia médica. 2017 Full text (link to original source) Full text (in our servers)
  3. MedlinePlus. Magnesium in diet. Medical Encyclopedia 2017 Full text (link to original source) Full text (in our servers)
  4. Dennis AT. Management of pre-eclampsia: issues for anaesthetists. Anaesthesia. 2012 Sep;67(9):1009-20. Abstract Full text (link to original source) Full text (in our servers)
  5. Hall Moran V, Lowe N, Crossland N, Berti C, Cetin I, Hermoso M, Koletzko B, Dykes F. Nutritional requirements during lactation. Towards European alignment of reference values: the EURRECA network. Matern Child Nutr. 2010 Oct;6 Suppl 2:39-54. Abstract Full text (link to original source) Full text (in our servers)
  6. Schaefer C, Peters P, Miller RK. Drugs During Pregnancy and Lactation. Treatment options and risk assessment. Elsevier, second edition. London. 2007
  7. Mahadevan U, Kane S. American gastroenterological association institute technical review on the use of gastrointestinal medications in pregnancy. Gastroenterology. 2006 Jul;131(1):283-311. Review. Abstract Full text (link to original source) Full text (in our servers)
  8. EFSA. European Food Safety Authority. Tolerable upper intake levels for vitamins and minerals. Scientific Committee on Food. 2006 Full text (link to original source) Full text (in our servers)
  9. Richter JE. Review article: the management of heartburn in pregnancy. Aliment Pharmacol Ther. 2005 Nov 1;22(9):749-57. Review. Abstract Full text (in our servers)
  10. Nice FJ, Snyder JL, Kotansky BC. Breastfeeding and over-the-counter medications. J Hum Lact. 2000 Nov;16(4):319-31. Review. Erratum in: J Hum Lact 2001 Feb;17(1):90. Abstract
  11. Dórea JG. Magnesium in human milk. J Am Coll Nutr. 2000 Apr;19(2):210-9. Review. Abstract
  12. Hagemann TM. Gastrointestinal medications and breastfeeding. J Hum Lact. 1998 Sep;14(3):259-62. Review. Abstract
  13. Broussard CN, Richter JE. Treating gastro-oesophageal reflux disease during pregnancy and lactation: what are the safest therapy options? Drug Saf. 1998 Oct;19(4):325-37. Review. Abstract
  14. Idama TO, Lindow SW. Magnesium sulphate: a review of clinical pharmacology applied to obstetrics. Br J Obstet Gynaecol. 1998 Mar;105(3):260-8. Review. No abstract available. Abstract
  15. Morris ME, LeRoy S, Sutton SC. Absorption of magnesium from orally administered magnesium sulfate in man. J Toxicol Clin Toxicol. 1987;25(5):371-82. Abstract
  16. Feeley RM, Eitenmiller RR, Jones JB Jr, Barnhart H. Calcium, phosphorus, and magnesium contents of human milk during early lactation. J Pediatr Gastroenterol Nutr. 1983 May;2(2):262-7. Abstract
  17. Cruikshank DP, Varner MW, Pitkin RM. Breast milk magnesium and calcium concentrations following magnesium sulfate treatment. Am J Obstet Gynecol. 1982 Jul 15;143(6):685-8. No abstract available. Abstract

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