Magnesium Oxide

Magnesium oxide is an antacid with general properties similar to those of magnesium hydroxide. It is also an osmotic laxative used for bowel preparation combined with bisacodyl or sodium picosulfate. It is used as an antacid combined with aluminum hydroxide to counteract the laxative effect. It is also used as a magnesium supplement in deficiency states and as a food additive. Oral administration.

Adequate magnesium intake for nursing mothers is estimated at 310 to 360 mg daily ^{(MedlinePlus 2017, EFSA 2006)}; some countries set values as high as 450 mg daily. ^{(Hall 2010)}

Aluminum and magnesium from antacids are not concentrated in breast milk. ^{(Mahadevan 2006, Richter 2005)}

The average natural concentration of magnesium in milk is 31 mg/L (15 to 64 mg/L) and is little affected by magnesium administration. ^{(Cruikshank 1982, Dórea 2000, Nagy 1994, Feeley 1983).}

Its low oral bioavailability ^{(AEMPS 2024)} means that the passage to infant plasma from ingested breast milk is scarce, except in premature infants and the immediate neonatal period, in which there may be greater intestinal absorption.

The manufacturer and expert authors consider its use compatible with breastfeeding. ^{(Hale, AEMPS 2024, Schaefer 2015, Mahadevan 2006, Richter 2005, Broussard 1998)}

Avoid chronic or excessive use. List of essential medicines WHO 2002: Aluminum and magnesium hydroxides compatible with breastfeeding. ^{(WHO 2002)}