Last update Sept. 27, 2014

Lactulose

Very Low Risk

Safe. Compatible. Minimal risk for breastfeeding and infant.

Disaccharide (galactose and fructose) which is barely absorbed by the small intestine and reaches the large intestine (colon) where it exerts its action as an osmotic laxative drug. A small amount that is absorbed is excreted unmodified in the urine.

At latest update were not found published data on excretion into breast milk. However, because it does not reach the mother's plasma, any concentration in the milk is not expected.

Medication with authorized indication in infants.

Alternatives

We do not have alternatives for Lactulose since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.
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Other names

Lactulose is also known as


Group

Lactulose belongs to this group or family:

Tradenames

Main tradenames from several countries containing Lactulose in its composition:

List of 6 tradenames

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 3 %
Molecular weight 342 daltons

References

  1. Gharehbaghi K, Gharehbaghi DR, Wierrani F, Sliutz G. [Treatment of Chronic Functional Constipation during Pregnancy and Lactation]. Z Geburtshilfe Neonatol. 2016 Abstract
  2. Mahadevan U, Kane S. American gastroenterological association institute technical review on the use of gastrointestinal medications in pregnancy. Gastroenterology. 2006 Jul;131(1):283-311. Review. Abstract Full text (link to original source) Full text (in our servers)
  3. Müller M, Jaquenoud E. [Treatment of constipation in pregnant women. A multicenter study in a gynecological practice]. Schweiz Med Wochenschr. 1995 Abstract
  4. Würsch P, Koellreutter B, Schweizer TF. Hydrogen excretion after ingestion of five different sugar alcohols and lactulose. Eur J Clin Nutr. 1989 Dec;43(12):819-25. Abstract

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