Last update Oct. 11, 2017
Limited compatibility
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Хлорзоксазон is Chlorzoxazone in Cyrillic.
Is written in other languages:Main tradenames from several countries containing Хлорзоксазон in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 100 | % |
Molecular weight | 170 | daltons |
Protein Binding | 13 - 18 | % |
VD | 0.5 ± 0.1 | l/Kg |
Tmax | 2 ± 0.8 | hours |
T½ | 1.1 ± 0.5 a 1.5 ± 0.3 | hours |
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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America
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Centrally-acting muscle relaxant with sedative properties. Administered orally.
It has pharmacokinetics with rapid absorption and elimination (PDR 2017, Prompila 2007, Desiraju 1983).
Since the last update we have not found published data about its excretion in breast milk.
Its pharmacokinetic data (low molecular weight, low protein binding, small volume of distribution) make its likely that it could pass into breast milk in quantities that could be significant.
If you have to use it during breastfeeding, you should monitor sedative effects in the baby. To minimize exposure, medication can be taken just after a feed and waiting 3-4 hours before breastfeeding again.