Last update Dec. 13, 2024

Kava, Kava-Kava

Incompatible

Very unsafe. Contraindicated. Use of an alternative or cessation of breastfeeding. Read the Commentary.

Perennial shrub native to Oceania. It contains kavapirones (styryl-lactones), chalcones, cinnamates and sterols. The dried rhizome is used.It has anxiolytic, hypnotic and myorelaxant properties. Oral administration. (Fitoterapia.net, IARC 2016 p 117-140, WHO 2002 p231-245)

As of the last update we found no published data on its excretion in breast milk.

May cause serious adverse effects (Posadzki 2013) and is possibly carcinogenic (group 2B) in humans. (IARC 2016 p 137)

The European Medicines Agency (EMA) has recommended the withdrawal from the market of products containing Kava, due to a high risk of hepatotoxicity causing fulminant hepatic failure. (Ballotin 2018, NLM 2018, Bunchorntavakul 2013, NLM 2012, Chitturi 2008)

The Spanish Ministry of Health and Consumption includes it in the list of plants whose sale to the public is prohibited or restricted due to its toxicity. (MSC 2004)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Kava, Kava-Kava in other languages or writings:

Group

Kava, Kava-Kava belongs to this group or family:

Tradenames

Main tradenames from several countries containing Kava, Kava-Kava in its composition:

References

  1. Fitoterapia.net. Vanaclocha B, Cañigueral S. Fitoterapia.net. 1992 - - Disponible en: https://www.fitoterapia.net. Consulted on Dec. 21, 2023 Abstract
  2. Ballotin VR, Bigarella LG, Brandão ABM, Balbinot RA, Balbinot SS, Soldera J. Herb-induced liver injury: Systematic review and meta-analysis. World J Clin Cases. 2021 Jul 16;9(20):5490-5513. Abstract Full text (link to original source)
  3. IARC - WHO. International Agency for research on Cancer. Some Drugs and Herbal Products. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans Volume 108. 2016 Full text (link to original source)
  4. Posadzki P, Watson LK, Ernst E. Adverse effects of herbal medicines: an overview of systematic reviews. Clin Med (Lond). 2013 Abstract Full text (link to original source)
  5. Bunchorntavakul C, Reddy KR. Review article: herbal and dietary supplement hepatotoxicity. Aliment Pharmacol Ther. 2013 Abstract Full text (link to original source) Full text (in our servers)
  6. NLM. Kava Kava. 2018 Apr 10. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. Abstract Full text (link to original source)
  7. Chitturi S, Farrell GC. Hepatotoxic slimming aids and other herbal hepatotoxins. J Gastroenterol Hepatol. 2008 Abstract Full text (in our servers)
  8. MSC - Ministerio de Sanidad y Consumo de España. ORDEN SCO/190/2004, de 28 de enero, por la que se establece la lista de plantas cuya venta al público queda prohibida o restringida por razón de su toxicidad. BOE 2004; 32:5061-6065 Full text (link to original source) Full text (in our servers)
  9. Zhou S, Koh HL, Gao Y, Gong ZY, Lee EJ. Herbal bioactivation: the good, the bad and the ugly. Life Sci. 2004 Abstract Full text (link to original source)
  10. WHO. World Health Organization. Geneva. WHO monographs on selected medicinal plants. Volume 2. WHO monographs. 2002 Full text (link to original source) Full text (in our servers)

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