Last update Nov. 23, 2023

J07AN01; L03AX03 

Very Low Risk

Safe. Compatible. Minimal risk for breastfeeding and infant.

The vaccine with live bacteria obtained from a strain derived from the bacillus Calmette and Guérin (Mycobacterium bovis, BCG) is used intradermally for active immunization against tuberculosis and intravesically in the treatment and prophylaxis of carcinoma in situ and recurrent bladder papillomas.

An breastfeeding mother with urothelial carcinoma was treated with intravesical BCG. The infant received intradermal BCG vaccine two weeks before treatment and there were no side effects for either mother or infant. (Barbur 2022)

This vaccine is commonly given to newborns and infants in many countries. (Montagnani 2016, Mittal 2014, Goh 1989)

The Centers for Disease Control and Prevention, health experts and several health organizations indicate that vaccines - whether from live attenuated, dead or inactivated microorganisms, or from subunits or toxoids of the same - when administered to breastfeeding mothers do not affect breastfeeding or the safety of mothers or infants and that breastfeeding is not a contraindication for the tuberculosis vaccine. (Sachs 2013, ACIP-MMWR 2011, Red Book 2021-24, Gruslin 2009, Clements 1996, ACIP-MMWR 1989)

Breastfeeding increases the immunogenicity of some vaccines (ACIP-MMWR 2011, Pabst 1997), such as BCG when administered on the first day of life. (Red Book 2021-24, Pabst 1989)

Breastfeeding women can and should be protected with recommended vaccines like other adults (Red Book 2009, Clements 1996)

Newborns and infants should be immunized according to current vaccination schedules, regardless of whether or not they are breastfed. (ACIP-MMWR 2011, Red Book 2021-24).

List of essential medicines WHO 2002: the BCG vaccine is compatible with breastfeeding. (WHO/UNICEF 2002).

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

J07AN01; L03AX03  is BCG Vaccines for tuberculosis in ATC Code/s.

Is written in other languages:

J07AN01; L03AX03  is also known as


  1. CDC- ACIP. Vaccine Recommendations and Guidelines of the ACIP. Special Situations. Breastfeeding and Vaccination. - 2023 Consulted on Oct. 25, 2023 Full text (link to original source)
  2. CDC - Centers for Disease Control and Prevention. Vaccination Safety for Breastfeeding Mothers. Breastfeeding and Special Circumstances. 2023 Full text (link to original source) Full text (in our servers)
  3. Barbur E, Doganca T, Obek C. Safe use of intravesical bacillus Calmette-Guérin immunotherapy for bladder cancer during breastfeeding: a case report. Immunotherapy. 2022 Jul;14(10):759-764. Abstract
  4. (Red Book). AAP. Kimberlin DW, Barnett ED, , Lynfield R, Sawyer MH eds. Red Book: 2021-2024. Report of the Committee on Infectious Diseases. 32th ed. Elk Grove Village, - 2021
  5. CAV-AEP. Comité asesor de vacunas de la Asociación Española de Pediatría. Lactancia materna y vacunas. None 2019 Full text (link to original source) Full text (in our servers)
  6. Montagnani C, Esposito S, Galli L, Chiappini E, Principi N, de Martino M; Italian Pediatric TB Study Group.. Recommendations for pediatric tuberculosis vaccination in Italy. Hum Vaccin Immunother. 2016 Abstract
  7. Briggs GG, Freeman RK, Towers CV, Forinash AB. Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk. Wolters Kluwer Health. Tenth edition (acces on line) 2015
  8. Mittal H, Das S, Faridi MM. Management of newborn infant born to mother suffering from tuberculosis: current recommendations & gaps in knowledge. Indian J Med Res. 2014 Abstract Full text (link to original source) Full text (in our servers)
  9. Sachs HC; Committee On Drugs. The transfer of drugs and therapeutics into human breast milk: an update on selected topics. Pediatrics. 2013 Sep;132(3):e796-809. Abstract Full text (link to original source) Full text (in our servers)
  10. CDC. National Center for Immunization and Respiratory Diseases. General recommendations on immunization --- recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 2011 Abstract Full text (in our servers)
  11. Gruslin A, Steben M, Halperin S, Money DM, Yudin MH; Infectious Diseases Committee of the Society of Obstetricians and Gynaecologists of Canada.. Immunization in pregnancy. J Obstet Gynaecol Can. 2009 Abstract
  12. WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Abstract Full text (link to original source) Full text (in our servers)
  13. Pickering LK, Granoff DM, Erickson JR, Masor ML, Cordle CT, Schaller JP, Winship TR, Paule CL, Hilty MD. Modulation of the immune system by human milk and infant formula containing nucleotides. Pediatrics. 1998 Feb;101(2):242-9. Abstract
  14. Pabst HF, Spady DW, Pilarski LM, Carson MM, Beeler JA, Krezolek MP. Differential modulation of the immune response by breast- or formula-feeding of infants. Acta Paediatr. 1997 Abstract
  15. Clements J. Opportunities to immunise. Child Health Dialogue. 1996 Abstract
  16. Goh TE, Low M, Chen CH, Tan TH. A comparative study of Japanese and British BCG vaccine strains in newborn infants. Asia Pac J Public Health. 1989 Abstract
  17. Pabst HF, Godel J, Grace M, Cho H, Spady DW. Effect of breast-feeding on immune response to BCG vaccination. Lancet. 1989 Abstract

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