Last update Sept. 2, 2022
Likely Compatibility
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Itopride Hydrochloride in other languages or writings:
Main tradenames from several countries containing Itopride Hydrochloride in its composition:
Variable | Value | Unit |
---|---|---|
Molecular weight | 395 | daltons |
Protein Binding | 96 | % |
pKa | 14.71 | - |
Tmax | 0.5 - 0.75 | hours |
T½ | 2.95 - 5.7 | hours |
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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
It is a prokinetic from the benzamide group, a dopamine antagonist and similar to Metoclopramide. Indicated in chronic gastritis and dyspepsia. Oral administration in 3 daily doses.
Since the last update we have not found published data on its excretion in breastmilk.
Its high plasma protein binding (Domínguez 2012) makes it unlikely to transfer into breastmilk in significant amounts.
It has very few bibliographical references, and is sold in few countries.
Until there is more published data on this drug in relation to breastfeeding, safer known alternatives may be preferable, especially during the neonatal period and in cases of prematurity.