Last update April 3, 2018

Iodinated Glycerol

High Risk

Poorly safe. Evaluate carefully. Use safer alternative or interrupt breastfeeding 3 to 7 T ½ (elimination half-lives). Read the Comment.

Producto yodado utilizado sin pruebas clínicas (Rubin 1996) como expectorante.

A fecha de última actualización no encontramos datos publicados sobre su excreción en leche materna.

Por su alto contenido de yodo puede provocar alteraciones de la función tiroidea (Gittoes 1995, Geurian 1994, Huseby 1991, Drinka 1998).

Fármaco con muy escasas referencias bibliográficas, comercializado en muy pocos países y retirado de otros por su potencial carcinogénesis en animales (FDA 1993).

Alternatives

  • Acetylcysteine ( Safe. Compatible. Minimal risk for breastfeeding and infant.)
  • Ambroxol ( Safe. Compatible. Minimal risk for breastfeeding and infant.)
  • Bromhexine ( Safe. Compatible. Minimal risk for breastfeeding and infant.)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

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José María Paricio, founder of e-lactancia.
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Other names

Iodinated Glycerol is also known as


Iodinated Glycerol in other languages or writings:

Group

Iodinated Glycerol belongs to this group or family:

Tradenames

Main tradenames from several countries containing Iodinated Glycerol in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 100 %
Molecular weight 258 daltons

References

  1. Rubin BK, Ramirez O, Ohar JA. Iodinated glycerol has no effect on pulmonary function, symptom score, or sputum properties in patients with stable chronic bronchitis. Chest. 1996 Abstract
  2. Gittoes NJ, Franklyn JA. Drug-induced thyroid disorders. Drug Saf. 1995 Abstract
  3. Geurian K, Branam C. Iodine poisoning secondary to long-term iodinated glycerol therapy. Arch Intern Med. 1994 Abstract
  4. FDA Removal of Organidin and Other Iodinated Glycerol containing Prescription Drug Products Sold as. Mucolytic-Expectorants from the Market. 1993 Full text (in our servers)
  5. Huseby JS, Bennett SW, Hagensee ME. Hyperthyroidism induced by iodinated glycerol. Am Rev Respir Dis. 1991 Abstract
  6. Drinka PJ, Nolten WE. Effects of iodinated glycerol on thyroid function studies in elderly nursing home residents. J Am Geriatr Soc. 1988 Abstract

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