Last update Aug. 25, 2019



Safe substance and/or breastfeeding is the best option.

A semisynthetic, inert and viscoelastic polymer with thickening, bioadhesive and solubility enhancing properties.
It is used as a pharmaceutical coating to modify its intestinal release and prolong its effect.
Used as a lubricant in the form of eye drops.

Since the last update we have not found published data on its excretion in breastmilk.

Since it is a derivative of cellulose, it is not absorbed either in the intestine or as an ophthalmological preparation (AEMPS 2014, MHRA 2009), so it is highly unlikely to appear in breastmilk. Its high molecular weight (Fukasawa 2004) makes its excretion in milk even less likely.

It is an inert product that is not metabolized and is devoid of toxicity, lacking systemic side effects (AEMPS 2014).


We do not have alternatives for Hypromellose since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.


Hypromellose belongs to this group or family:


Main tradenames from several countries containing Hypromellose in its composition:


Variable Value Unit
Oral Bioavail. 0 %
Molecular weight 13.000 - 20.000 daltons


  1. AEMPS-Stada. Hipromelosa. Ficha técnica. 2014 Full text (in our servers)
  2. MHRA. Hypromellose. Drug Summary. 2009 Full text (in our servers)
  3. Fukasawa M, Obara S. Molecular weight determination of hypromellose acetate succinate (HPMCAS) using size exclusion chromatography with a multi-angle laser light scattering detector. Chem Pharm Bull (Tokyo). 2004 Abstract

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e-lactancia is a resource recommended by El Parto Es Nuestro of Spain

Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM