Last update Jan. 4, 2022

Hepatitis B immunoglobulin

Compatible

Safe substance and/or breastfeeding is the best option.

Immunoglobulins (Ig) are proteins produced by B lymphocytes as a humoral response to antigens foreign to the body itself. The immunoglobulins used in clinical practice are preparations from human serum or plasma that contain antibodies, mainly IgG. 

Human Hepatitis B Immunoglobulin mainly contains immunoglobulin G (IgG) with a high content of specific antibodies against hepatitis B surface antigen. it is obtained from plasma of selected and / or immunized donors who have specific antibodies against hepatitis B surface antigen.

Its very high molecular weight make it highly unlikely that significant quantities will pass into breast milk. Administration of standard immunoglobulin does not significantly alter the levels of immunoglobulins (IgG or IgM) in colostrum or breast milk. (Palmeira 2009)

Expert authors consider the use of this medication safe during breastfeeding. (LactMed, Briggs 2015)

List of WHO essential medicines: Human Immunoglobulins are compatible with breastfeeding. (WHO / UNICEF 2002)


See below the information of these related products:

Alternatives

We do not have alternatives for Hepatitis B immunoglobulin since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Hepatitis B immunoglobulin is also known as


Hepatitis B immunoglobulin in other languages or writings:

Group

Hepatitis B immunoglobulin belongs to this group or family:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 0 %
Molecular weight ≈ 150.000 daltons

References

  1. Briggs GG, Freeman RK, Towers CV, Forinash AB. Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk. Wolters Kluwer Health. Tenth edition (acces on line) 2015
  2. Palmeira P, Costa-Carvalho BT, Arslanian C, Pontes GN, Nagao AT, Carneiro-Sampaio MM. Transfer of antibodies across the placenta and in breast milk from mothers on intravenous immunoglobulin. Pediatr Allergy Immunol. 2009 Sep;20(6):528-35. Abstract
  3. CDC-ACIP. Protection Against Viral Hepatitis Recommendations of the Immunization Practices Advisory Committee (ACIP). Recommendations and Reports. 1990 Full text (link to original source) Full text (in our servers)

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