Last update Sept. 6, 2025

ハルパゴフィツム属 , 悪魔のかぎ爪

Likely Compatibility

Fairly safe. Mild or unlikely adverse effects. Compatible under certain circumstances. Follow-up recommended. Read Commentary.

The root of this herb that is native from Southern Africa is used. It contains iridoids as harpagoside and phytosterols and flavonoids. Traditional indications are not based on clinical evidence: relief of pain and joint inflammation, dyspepsia, flatulence and anorexia (Bargsten 2025, EMA 2016, Cameron 2014, WHO 2007, Brien 2006) . Similar efficacy to meloxicam has been found in the treatment of knee osteoarthritis. (Farpour 2021)

As of last update we found no published data on its excretion in breast milk.

Side effects are rare and usually mild (Posadzki 2013, Vlachojannis 2008); cases of gastralgia and dyspepsia (Prescrire 2013) and pancreatitis have been published. (Douros 2013)

Moderate or occasional consumption would be acceptable during breastfeeding.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

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José María Paricio, founder of e-lactancia.

Other names

ハルパゴフィツム属 , 悪魔のかぎ爪 is Devil’s Claw Root in Japanese.

Is written in other languages:

ハルパゴフィツム属 , 悪魔のかぎ爪 is also known as

Group

ハルパゴフィツム属 , 悪魔のかぎ爪 belongs to this group or family:

Tradenames

Main tradenames from several countries containing ハルパゴフィツム属 , 悪魔のかぎ爪 in its composition:

References

  1. Bargsten FE, Seifert R. Devil's claw (Harpagophytum procumbens): is the buzz in Google justified? Naunyn Schmiedebergs Arch Pharmacol. 2025 Aug;398(8):10823-10842. Abstract Full text (link to original source)
  2. Farpour HR, Rajabi N, Ebrahimi B. The Efficacy of Harpagophytum procumbens (Teltonal) in Patients with Knee Osteoarthritis: A Randomized Active-Controlled Clinical Trial. Evid Based Complement Alternat Med. 2021 Oct 19;2021:5596892. Abstract Full text (link to original source)
  3. EMA European Union herbal monograph on Harpagophytum procumbens DC. and/or Harpagophytum zeyheri Decne., radix Committee on Herbal Medicinal Products (HMPC) 2016 Full text (in our servers)
  4. Cameron M, Chrubasik S. Oral herbal therapies for treating osteoarthritis. Cochrane Database Syst Rev. 2014 May 22;2014(5):CD002947. Abstract Full text (link to original source)
  5. Posadzki P, Watson LK, Ernst E. Adverse effects of herbal medicines: an overview of systematic reviews. Clin Med (Lond). 2013 Abstract Full text (link to original source)
  6. Douros A, Bronder E, Andersohn F, Klimpel A, Thomae M, Ockenga J, Kreutz R, Garbe E. Drug-induced acute pancreatitis: results from the hospital-based Berlin case-control surveillance study of 102 cases. Aliment Pharmacol Ther. 2013 Abstract
  7. [No authors listed] Devil's claw root: ulcers and gastrointestinal bleeding? Prescrire Int. 2013 Abstract
  8. Cordier W, Steenkamp V. Drug interactions in African herbal remedies. Drug Metabol Drug Interact. 2011 Abstract
  9. Vlachojannis J, Roufogalis BD, Chrubasik S. Systematic review on the safety of Harpagophytum preparations for osteoarthritic and low back pain. Phytother Res. 2008 Abstract
  10. WHO. World Health Organization. Geneva. WHO monographs on selected medicinal plants. Volume 3. WHO monographs. 2007 Full text (link to original source) Full text (in our servers)
  11. Brien S, Lewith GT, McGregor G. Devil's Claw (Harpagophytum procumbens) as a treatment for osteoarthritis: a review of efficacy and safety. J Altern Complement Med. 2006 Abstract

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