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Ulobetasol is a very high potency topical corticosteroid, structurally related to clobetasol. It is used in severe plaque psoriasis and corticosteroid-sensitive dermatoses.
At the date of last update we found no published data on its excretion in breast milk.
The small dose and low plasma absorption of most topical dermatological preparations make passage of significant amounts into breast milk unlikely.
Since it is a high potency corticosteroid, the baby's skin should not come into direct contact with the areas of maternal skin that have been treated.
High potency corticosteroids should not be applied to the nipple, but choose the least potent corticosteroid, apply it just after the feeding is over so that it is reabsorbed before the next feeding and, if necessary, remove the remains with a gauze.
They should not be used for more than one week at a time. Serious clinical involvement has been reported in an infant whose mother applied a corticosteroid to the nipple continuously. (De Stefano 1983)
The application of creams, gels and other locally applied products containing paraffin (mineral oil) on the nipple should be avoided so that the infant does not absorb it. (Concin 1988, Noti 1983)
Various medical societies and expert authors consider corticosteroids, topical, systemic, inhaled, oral, nasal, ophthalmic, or rectal, to be safe and compatible with breastfeeding.
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