Last update March 28, 2014

Fluorodeoxyglucose F18, 18F-FDG

High Risk

Poorly safe. Evaluate carefully. Use safer alternative or interrupt breastfeeding 3 to 7 T ½ (elimination half-lives). Read the Comment.

Radiation from a PET scan test is not higher than that from an abdominal CAT scan test.

Small quantity and short half life span of radionuclides used for this test make it safe to nurse the baby shortly after the test is done. Overall, it is safe to stop nursing for a 5 to 6 of isotope half life period which is the time require for the complete disappereance of radioactivity from the body.

Half life spans . . . . . . . . . . . . . . . . . Breastfeeding interruption time

F-18: 110 minutes . . . . . . . . . . . . . . . . . 10 hours (avoid contact for the first 4 hours)

C-11: 20 minutes . . . . . . . . . . . . . . . . . . . 2 hours

N-13: 10 minutes . . . . . . . . . . . . . . . . . . . 1 hour

O-15: 2 minutes . . . . . . . . . . . . . . . . . . . 10 minutes

Rb-82: 1,3 minutes . . . . . . . . . . . . . . . . . . 8 minutes

Meanwhile the half life span goes by milk pumping and freezing is recommended: it is safe to use the milk after a 10 half life span period.

Alternatives

We do not have alternatives for Fluorodeoxyglucose F18, 18F-FDG.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

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Other names

Fluorodeoxyglucose F18, 18F-FDG is also known as Positron Emission Tomography. Here it is a list of alternative known names::


Group

Fluorodeoxyglucose F18, 18F-FDG belongs to this group or family:

References

  1. ACMUI: Advisory Committee on Medical Uses of Isotopes. Sub-Committee on Nursing Mother Guidelines for the Medical Administration of Radioactive Materials. Final Report Submitted: January 31, 2019 Full text (link to original source)
  2. Mitchell KB, Fleming MM, Anderson PO, Giesbrandt JG; Academy of Breastfeeding Medicine.. ABM Clinical Protocol #30: Radiology and Nuclear Medicine Studies in Lactating Women. Breastfeed Med. 2019 Jun;14(5):290-294. Abstract
  3. ICRP 2015: Mattsson S, Johansson L, Leide Svegborn S, Liniecki J, Noßke D, Riklund KÅ, Stabin M, Taylor D, Bolch W, Carlsson S, Eckerman K, Giussani A, Söderberg L, Valind S; ICRP.. Radiation Dose to Patients from Radiopharmaceuticals: a Compendium of Current Information Related to Frequently Used Substances. ANNEX D. RECOMMENDATIONS ON BREAST-FEEDING INTERRUPTIONS. ICRP Publication 128. Ann. ICRP 44(2S). 2015. Table D1 p320-21. Abstract Full text (link to original source)
  4. Ko KH, Jung HK, Jeon TJ. Diffuse intense 18F-FDG uptake at PET in unilateral breast related to breastfeeding practice. Korean J Radiol. 2013 Abstract Full text (in our servers)
  5. Jamar F, Buscombe J, Chiti A, Christian PE, Delbeke D, Donohoe KJ, Israel O, Martin-Comin J, Signore A. EANM/SNMMI guideline for 18F-FDG use in inflammation and infection. J Nucl Med. 2013 Abstract Full text (in our servers)
  6. Abhyankar A, Joshi J, Basu S. FDG uptake in unilateral breast related to breastfeeding practice in a patient of pulmonary hydatid cyst. Clin Nucl Med. 2012 Abstract
  7. Segall G, Delbeke D, Stabin MG, Even-Sapir E, Fair J, Sajdak R, Smith GT; SNM. SNM practice guideline for sodium 18F-fluoride PET/CT bone scans 1.0. J Nucl Med. 2010 Abstract Full text (in our servers)
  8. Devine CE, Mawlawi O. Radiation safety with positron emission tomography and computed tomography. Semin Ultrasound CT MR. 2010 Abstract
  9. Leide-Svegborn S. Radiation exposure of patients and personnel from a PET/CT procedure with 18F-FDG. Radiat Prot Dosimetry. 2010 Abstract
  10. Hendler D, Stemmer SM. Uncommon reason for high fluorodeoxyglucose positron emission tomography uptake. J Clin Oncol. 2010 Abstract Full text (in our servers)
  11. ICRP. Radiation dose to patients from radiopharmaceuticals. Addendum 3 to ICRP Publication 53. ICRP Publication 106. Annex D. Recommendations on breast-feeding interruptions, p. 163-165. Ann ICRP. 2008 Abstract Full text (link to original source) Full text (in our servers)
  12. Moses-Kolko EL, Meltzer CC, Helsel JC, Sheetz M, Mathis C, Ruszkiewicz J, Bogen D, Confer AL, Wisner KL. No interruption of lactation is needed after (11)C-WAY 100635 or (11)C-raclopride PET. J Nucl Med. 2005 Abstract Full text (in our servers)
  13. . Anthony Parker, Margaret E. Daube-Witherspoon, L. Stephen Graham, Henry D. Royal, Andrew E. Todd-Pokropek, Michael V. Yester. Society of Nuclear Medicine Procedure Guideline for General Imaging. Society of Nuclear Medicine. 2004 Full text (in our servers)
  14. Hicks RJ, Binns D, Stabin MG. Pattern of uptake and excretion of (18)F-FDG in the lactating breast. J Nucl Med. 2001 Abstract Full text (in our servers)

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