Last update Feb. 13, 2022
Compatible
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Fluocortolone is also known as
Fluocortolone in other languages or writings:
Fluocortolone belongs to these groups or families:
Main tradenames from several countries containing Fluocortolone in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | oral: 80; derm.: poor. baja | % |
Molecular weight | 377 | daltons |
Protein Binding | 83 - 95 | % |
VD | 1.03 | l/Kg |
pKa | 13.84 | - |
Tmax | 1.4 - 2.1 | hours |
T½ | 1.25 - 1.76 | hours |
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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Glucocorticoid of moderate potency used topically in skin problems. Can also be administered orally.
Although at the date of the last revision there are no published data in relation to breastfeeding, the low absorption through the skin makes it unlikely that a significant amount will pass into breast milk. (Butler 2014, Westermann 2012)
In addition, systemic glucocorticoids, at usual doses, do not contraindicate breastfeeding (Butler 2014, WHO 2002, AAP 2001). Corticosteroids, in the form of cortisol, are a natural component of colostrum and breast milk. (Kulsky 1981)
If used, do not apply on the breast or large areas or for prolonged periods to avoid systemic absorption.
If they are required to treat eczema or dermatosis of the nipple, it is advisable to choose the less powerful corticosteroid, apply it just after finishing the intake so that it has been reabsorbed before the next one; if necessary remove remains with gauze and do not use for more than a week.
It is recommended to avoid using on the nipple creams, gels and other products intended for use on skin that may contain paraffin (mineral oil) in order to keep from absorption the infant. (Concin 2008, Noti 2003)
The American Academy of Pediatrics considers systemic corticosteroids to be compatible with lactation, recommending prednisone or prednisolone because they are known to be poorly excreted in breast milk. (AAP 2001)
WHO 2002 essential medicines list: Prednisolone is compatible with breastfeeding. (WHO 2002)