Last update Jan. 21, 2014


High Risk

Poorly safe. Evaluate carefully. Use safer alternative or interrupt breastfeeding 3 to 7 T ½ (elimination half-lives). Read the Comment.

On latest update relevant data on breastfeeding was not found.

Pharmacokinetic data (high molecular weight but low protein binding) indicates that drug excretion into breast milk would be moderately high. Low oral biodisponibility would be protective for breastfed children who are not newborn or premature.

Until new data is available nursing should be delayed for a 5-half lives period (150 hours - 6 to 7 days) after last intake.


  • Azathioprine ( Safe. Compatible. Minimal risk for breastfeeding and infant.)
  • Ciclosporin ( Safe. Compatible. Minimal risk for breastfeeding and infant.)
  • Tacrolimus ( Safe. Compatible. Minimal risk for breastfeeding and infant.)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.


Everolimus belongs to these groups or families:


Main tradenames from several countries containing Everolimus in its composition:


Variable Value Unit
Oral Bioavail. 30 %
Molecular weight 958 daltons
Protein Binding 74 %
VD 1.6 l/Kg
Tmax 1 - 2 hours
30 hours


  1. Constantinescu S, Pai A, Coscia LA, Davison JM, Moritz MJ, Armenti VT. Breast-feeding after transplantation. Best Pract Res Clin Obstet Gynaecol. 2014 Nov;28(8):1163-73. Abstract
  2. Everolimus Drug Summary 2013 Full text (in our servers)
  3. Everolimus Ficha técnica 2013 Full text (in our servers)

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e-lactancia is a resource recommended by El Parto Es Nuestro of Spain

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