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It is a potent loop diuretic with actions and uses similar to those of furosemide. It is used in the treatment of edema and ascites associated with heart failure, liver cirrhosis, and kidney disease. Oral or intravenous administration.
At the date of the last update we did not find any published data on its excretion in breast milk.
Its high binding to plasma proteins makes it difficult to pass into breast milk.
An intense diuresis that decreases plasma volume could decrease milk production. Long-term treatment with diuretic drugs (particularly those Thiazides with long lasting effect and loop-acting drugs) may inhibit lactation. Use a lower dose as possible, especially during the first postnatal month.