Last update July 15, 2017

Escin

Compatible

Safe substance and/or breastfeeding is the best option.

Saponin which is contained in Horse Chestnut seeds (see specific info) and usual topically used as antivaricose and venoprotector.

At latest update no published data on excretion into breast milk was found.

A high molecular weight makes it unlikely its pass to breast milk in significant amounts.
Do not apply on the chest or thoroughly clean it up before breastfeeding.
The Commission E of German Ministry of Health has approved its use during lactation.

Given its lack of toxicity at normal doses, a moderate consumption during lactation would pose a very low risk.


See below the information of this related product:

  • Horse Chestnut (Safe substance and/or breastfeeding is the best option.)

Alternatives

We do not have alternatives for Escin since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

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Other names

Escin is also known as Aescin.


Escin in other languages or writings:

  • C55H86O24 (Molecular formula)

Group

Escin belongs to this group or family:

Tradenames

Main tradenames from several countries containing Escin in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. Baja - Poor %
Molecular weight 1131 daltons

References

  1. Zając M, Wiśniewski M, Sein Anand J. [Intoxication by powdered seeds of horse chestnut (Aesculus hippocastanum) used nasally as snuff - a case report]. Przegl Lek. 2014 Abstract
  2. Pittler MH, Ernst E. Horse chestnut seed extract for chronic venous insufficiency. Cochrane Database Syst Rev. 2012 Abstract
  3. DGF. Dirección General de Farmacia. Servicio Canario de la Salud. Listado de fármacos considerados de Utilidad terapéutica Baja (UTB). None 2011 Full text (in our servers)
  4. Methlie CB, Schjøtt J. [Horse chestnut--remedy for chronic venous insufficiency]. Tidsskr Nor Laegeforen. 2009 Abstract
  5. Pittler MH, Ernst E. Horse chestnut seed extract for chronic venous insufficiency. Cochrane Database Syst Rev. 2004 Abstract
  6. Siebert U, Brach M, Sroczynski G, Berla K. Efficacy, routine effectiveness, and safety of horsechestnut seed extract in the treatment of chronic venous insufficiency. A meta-analysis of randomized controlled trials and large observational studies. Int Angiol. 2002 Abstract

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