Last update Dec. 21, 2022
Compatible
We do not have alternatives for Efavirenz (EFV) since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Efavirenz (EFV) in other languages or writings:
Main tradenames from several countries containing Efavirenz (EFV) in its composition:
Write us at elactancia.org@gmail.com
e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Antiretroviral. It is a non-nucleoside reverse transcriptase inhibitor (NNRTI) with activity against HIV-1 used with other antiretrovirals for combination therapy of HIV infection and AIDS. Oral administration once a day.
It is excreted in breast milk in clinically insignificant amounts. (Aebi 2022, Oumar 2018, Palombi 2016, Olagunju 2015, Schneider 2008)
No problems have been observed in infants whose mothers have taken it. (Kapito 2021, Oumar 2018, Olagunju 2015, Cohan 2015, Schneider 2008
Plasma levels in these infants were very low, 9% to 13% of maternal plasma levels. (Aebi 2022, Oumar 2018, Palombi 2016, Olagunju 2015, Gandhi 2013, Schneider 2008)
Several medical societies and expert authors consider the use of this medication to be safe during breastfeeding. (WHO 2016 y 2014, Pandhi 2014, Hirnschall 2013)