Last update March 19, 2020

E466

Compatible

Safe substance and/or breastfeeding is the best option.

A semisynthetic polymer derived from cellulose, inert and viscoelastic with thickening, bioadhesive and solubility enhancing properties.
It is used as a drug coating in order to modify its intestinal release and prolong its effect, in preparations for wounds, as artificial saliva and as a lubricant in the form of eye drops.

Since the last update we have not found published data on its excretion in breastmilk.

Being a cellulose derivative, it is not absorbed in the intestine, or as an ophthalmological preparation (AEMPS 2018), so it is highly unlikely to appear in breastmilk.
Its high molecular weight still makes its excretion in breastmilk unlikely.

It is an inert product that is not metabolized and is devoid of toxicity, lacking systemic side effects.

The manufacturer considers the use of this medication to be safe during breastfeeding (AEMPS 2018, Allergan 2014).

Alternatives

We do not have alternatives for E466 since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

E466 is Carmellose in E number.

Is written in other languages:

E466 is also known as

Tradenames

Main tradenames from several countries containing E466 in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 0 %
Molecular weight 54.083 daltons

References

  1. AEMPS-Stada. Carmelosa. Ficha técnica. 2018 Full text (in our servers)
  2. Allergan. Carmellose (Celluvisc). Drug Summary. 2014 Full text (in our servers)

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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America

Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM