Last update Sept. 4, 2022
It is a first generation antihistamine drug which is related to ethanolamine, with sedative and anti-muscarinic effects. It has been used as hypnotic and for vomiting relief. Oral administration one to three times a day.
At latest update, relevant published data on excretion into breast milk were not found.
Pharmacokinetic characteristics would favour that it may be excreted into breast milk in significant amount.
On a telephone survey, 10% of infants whose mothers were on several types of antihistamine medication have suffered of colicky pain and irritability that disappeared without treatment. (Ito 1993)
For both treatment of mothers and infants would be safer the use of tested antihistamine medication without sedative effect, especially in prematures and infants younger than 1 month of age.
Whenever used while breastfeeding, the use of the lower effective dose and for the shortest time as possible is recommended. Follow-up for somnolence and feeding troubles should be warranted.
Bed-sharing with the baby is not recommended if drugs are used due to increased risk of suffocation or sudden infant death. (ABM 2020 & 2008, UNICEF 2018, 2017, 2014 y 2013, Landa 2012, UNICEF 2006)
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2012 of United States of America
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