Last update Aug. 5, 2022
Very Low Risk
We do not have alternatives for Dioxipregnen; Pregnenedione since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Dioxipregnen; Pregnenedione is also known as Progesterone. Here it is a list of alternative known names::
Dioxipregnen; Pregnenedione in other languages or writings:
Dioxipregnen; Pregnenedione belongs to these groups or families:
Main tradenames from several countries containing Dioxipregnen; Pregnenedione in its composition:
|Oral Bioavail.||Baja - Low||%|
|Protein Binding||96 - 99||%|
|Tmax||Oral: 2 - 6 / vaginal: 25 -50||hours|
|T½||0.1 - 0.3||hours|
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e-lactancia is a resource recommended by Asociación Pro Lactancia Materna (APROLAM) of Mexico
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
It is a natural hormone secreted by the ovaries, adrenal glands and placenta. The synthetic form is used in contraception, control of abnormal uterine bleeding, maintenance of pregnancy, and prevention of endometrial hyperplasia. Oral, vaginal, intramuscular administration or as a component of an intrauterine device .
Excreted into breast milk in a non-significant amount. (Croxatto 1987)
No problems have been observed in infants whose mothers have taken it. (Wamboldt 2021, Roy 2020, Reisman 2018, Massai 1999, Chen 1998, Díaz 1997, Shaaban 1991, Díaz 1985 y 1984, Croxatto 1982)
The plasma levels in those infants have been undetectable or very low. (Croxatto 1987)
Progesterone does not affect the production of breast milk or the establishment and duration of breastfeeding. (Carr 2016, Allen 2016, Phillips 2016, Berens 2015, Massai 2005 y 1999, Sivin 1997)
During lactation progestin-only contraceptives are preferable to combined contraceptives. During the first 4 to 6 weeks after birth, non-hormonal methods are of choice as contraceptives. If associated to estrogens may inhibit lactation. It is recommended the use of contraceptive medication that does not contain estrogens, or, better if it contains progestogen alone. (Berens 2015, CDC 2013, Rowe 2013, Amir 2011, Erkkola 2005, WHO 1994)
American Academy of Pediatrics: medication usually compatible with breastfeeding. (AAP 2001)