Last update Oct. 29, 2024

Dimetindene Maleate (Topical use)

Compatible

Safe product and/or breastfeeding is the best option.

1st generation antihistamine, alkylamine derivative, with sedative and antimuscarinic effect. It is used in the form of gel or cream to calm cutaneous pruritus. 

At the date of last update, we did not find published data on its excretion in breast milk. 

The low cutaneous absorption (Radler 1995) and the high binding to plasma proteins make it unlikely that a significant amount will pass into breast milk.

Do not apply on the breast to avoid ingestion by the infant; if necessary, apply after a feeding and clean well with water before the next feeding. 

Systemic use (oral, nasal inhalation or intravenous) during lactation may have risks.


See below the information of this related product:

Alternatives

We do not have alternatives for Dimetindene Maleate (Topical use) since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.
DONATE NOW

Other names

Dimetindene Maleate (Topical use) in other languages or writings:

Group

Dimetindene Maleate (Topical use) belongs to this group or family:

Tradenames

Main tradenames from several countries containing Dimetindene Maleate (Topical use) in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. Dermal: 10 %
Molecular weight 409 daltons
Protein Binding 90 %
T½ 6 hours

References

  1. AEMPS. Dimetindeno emulsión Ficha técnica. 2000 Full text (in our servers)
  2. Radler S, Blaschke G. Transdermal absorption of dimethindene in man. Arch Pharm (Weinheim). 1995 Abstract

Total visits

32,903

Help us improve this entry

How to cite this entry

Do you need more information or did not found what you were looking for?

   Write us at elactancia.org@gmail.com

e-lactancia is a resource recommended by IHAN of Spain

Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM