Last update Nov. 11, 2020

Diloxanide Furoate

Likely Compatibility

Fairly safe. Mild or unlikely adverse effects. Compatible under certain circumstances. Follow-up recommended. Read Commentary.

Intra-lumen amebicide drug that is used alone or in combination with Metronidazole.
Oral administration 3 times a day for 10 days.

Since the last update we have not found any published data on its excretion in breast milk.

The paucity of available pharmacokinetic data (Drug 2020, CECMED 2015) does not allow predicting the amount of its possible excretion in human milk.

A mild side effect like flatulence observed among treated patients does not represent any risk for the child. No untoward effect on infants has been reported.

It may be given to children from the age of 1 month (BNF 2019 p325).

It is considered an essential medicine by the WHO (WHO 2002).

Alternatives

We do not have alternatives for Diloxanide Furoate.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

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Other names

Diloxanide Furoate in other languages or writings:

Group

Diloxanide Furoate belongs to this group or family:

Tradenames

Main tradenames from several countries containing Diloxanide Furoate in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 90 %
Molecular weight 328 daltons
pKa 9.39 -
Tmax 1 - 2 hours
T½ 3 - 6 hours

References

  1. Drug.com. Diloxanide. Drug Summary. 2020 Full text (in our servers)
  2. BNF. British National Formulary for Children 2018-2019 2018
  3. CECMED. Diloxanida. Ficha técnica. 2015 Full text (in our servers)
  4. WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Abstract Full text (link to original source) Full text (in our servers)

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