Last update Nov. 21, 2022
Likely Compatibility
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Digitoxin in other languages or writings:
Main tradenames from several countries containing Digitoxin in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 100 | % |
Molecular weight | 765 | daltons |
Protein Binding | > 90 | % |
pKa | 7.18 | - |
Tmax | 4 | hours |
T½ | 138 (77 - 234) | hours |
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e-lactancia is a resource recommended by IHAN of Spain
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
It is a digitalis glycoside with actions similar to those of digoxin that is used in the treatment of congestive heart failure and some cardiac arrhythmias. Oral or intravenous administration.
At the date of the last update, we found no published data on its excretion in breast milk.
Its high molecular weight and high binding to plasma proteins make its passage into breast milk unlikely, although its very long half-life (Haustein 1981) could favor it.
Until more published data is known about this drug in relation to breastfeeding, known safer alternatives are preferable, especially during the neonatal period and in the event of prematurity.