Last update Jan. 12, 2023

Diastase

Very Low Risk

Safe. Compatible. Minimal risk for breastfeeding and infant.

Amylases are enzymes that catalyze the hydrolysis of polysaccharides such as starch or glycogen into simple sugars: dextrins, oligosaccharides and monosaccharides, maltose, and glucose. They are produced in the pancreas and salivary glands. There are amylases of vegetable or microbial origin (Bacillus subtilis, Aspergillus oryzae and barley malt). They are used in the baking, brewing and fermentation industries and in medicine for their putative anti-inflammatory activity of the respiratory tract and local oedema. Pancreatin and pancrelipase have amylase activity. Oral administration.

At the date of the last update we did not find any published data on its excretion in breast milk.

La amilasa actúa localmente en el tracto gastrointestinal y no se absorbe en cantidades significativas.

Its high molecular weight and poor intestinal absorption make it highly unlikely a significant passage to the milk.

La leche materna contiene amilasa. (Dewit 1990, Hegardt  1984, Lindberg 1982)

Alternatives

We do not have alternatives for Diastase since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Diastase is also known as Amylase. Here it is a list of alternative known names::


Diastase in other languages or writings:

Tradenames

Main tradenames from several countries containing Diastase in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. ≈ 0 %
Molecular weight 50.000 - 100.000 daltons

References

  1. Dewit O, Dibba B, Prentice A. Breast-milk amylase activity in English and Gambian mothers: effects of prolonged lactation, maternal parity, and individual variations. Pediatr Res. 1990 Nov;28(5):502-6. Abstract
  2. Hegardt P, Lindberg T, Börjesson J, Skude G. Amylase in human milk from mothers of preterm and term infants. J Pediatr Gastroenterol Nutr. 1984 Sep;3(4):563-6. Abstract
  3. Lindberg T, Skude G. Amylase in human milk. Pediatrics. 1982 Aug;70(2):235-8. Abstract

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