Last update Jan. 19, 2024

Dengue Fever Vaccines

Likely Compatibility

Fairly safe. Mild or unlikely adverse effects. Compatible under certain circumstances. Follow-up recommended. Read Commentary.

Recombinant live attenuated tetravalent dengue vaccine for use in persons residing in dengue-endemic areas who have laboratory confirmation of previous dengue infection. (Red Book 2021-24 p303)

As of the last update, we found no published data on the excretion of Dengue vaccinia virus in breast milk.

Although it has been suggested (Van de Perre 2021), transmission of Dengue virus by breastfeeding has not been clearly demonstrated. (Mann 2018, Chen 2016)

The safety and efficacy of this vaccine in persons living in areas where dengue is not endemic and traveling to areas with endemic infection has not been established. (Red Book 2021-24 p304)

Expert authors believe that if a nursing mother requires dengue vaccine, this is not a reason to discontinue breastfeeding. (LactMed)

VACCINES AND BREASTFEEDING:

(RedBook 2021-2024, CDC 2023, 2011 y 2000, Taylor 2019, Lawrence 2016 p402, Sachs 2013, Munoz 2013, Raney 2012, Chen 2010, Schmidt 2004, Pabst 1997)

Vaccines are compatible with lactation, both live attenuated microorganisms and killed, inactivated or formed by parts or toxoids of the same or generated by recombinant technology.

They do not pass into milk, except for rubella, which does not usually infect the infant or only mildly, and do not cause problems in infants, except for yellow fever in infants under 6 months of age. 

Breastfeeding may improve the antibody response of vaccines and cause fewer side effects such as fever or anorexia. 

Immediate postpartum is the best time to vaccinate measles-rubella-mumps and varicella in women who were not immunized.

Breastfeeding women can and should be protected with the recommended vaccines as other adults.

Breastfed infants should be immunized according to the appropriate immunization schedule.


See below the information of this related product:

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

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José María Paricio, founder of e-lactancia.
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Other names

Dengue Fever Vaccines in other languages or writings:

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Tradenames

Main tradenames from several countries containing Dengue Fever Vaccines in its composition:

References

  1. LactMed. Drugs and Lactation Database (LactMed). Internet. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/ 2006 - Consulted on April 16, 2024 Full text (link to original source)
  2. CDC- ACIP. Vaccine Recommendations and Guidelines of the ACIP. Special Situations. Breastfeeding and Vaccination. - 2023 Consulted on Oct. 25, 2023 Full text (link to original source)
  3. Van de Perre P, Molès JP, Nagot N, Tuaillon E, Ceccaldi PE, Goga A, Prendergast AJ, Rollins N. Revisiting Koch's postulate to determine the plausibility of viral transmission by human milk. Pediatr Allergy Immunol. 2021 Jul;32(5):835-842. Abstract Full text (link to original source)
  4. (Red Book). AAP. Kimberlin DW, Barnett ED, , Lynfield R, Sawyer MH eds. Red Book: 2021-2024. Report of the Committee on Infectious Diseases. 32th ed. Elk Grove Village, - 2021
  5. Taylor CM, Shelton CM. Vaccine recommendations in pregnancy and lactation. J Am Pharm Assoc (2003). 2019 Jan - Feb;59(1):137-140. Abstract
  6. Mann TZ, Haddad LB, Williams TR, Hills SL, Read JS, Dee DL, Dziuban EJ, Pérez-Padilla J, Jamieson DJ, Honein MA, Shapiro-Mendoza CK. Breast milk transmission of flaviviruses in the context of Zika virus: A systematic review. Paediatr Perinat Epidemiol. 2018 Jul;32(4):358-368. Abstract Full text (link to original source) Full text (in our servers)
  7. Chen LH, Wilson ME. Update on non-vector transmission of dengue: relevant studies with Zika and other flaviviruses. Trop Dis Travel Med Vaccines. 2016 Aug 29;2:15. Abstract Full text (link to original source)
  8. Lawrence RA, Lawrence RM. Breastfeeding. A guide for the medical profession. Eighth Edition. Philadelphia: Elsevier; 2016
  9. Sachs HC; Committee On Drugs. The transfer of drugs and therapeutics into human breast milk: an update on selected topics. Pediatrics. 2013 Sep;132(3):e796-809. Abstract Full text (link to original source) Full text (in our servers)
  10. Munoz FM. Maternal immunization: an update for pediatricians. Pediatr Ann. 2013 Abstract
  11. Raney EC, El-Ibiary SY. Immunizations and pregnancy: an update for pharmacists. J Am Pharm Assoc (2003). 2012 Abstract
  12. Chen LH, Zeind C, Mackell S, LaPointe T, Mutsch M, Wilson ME. Breastfeeding travelers: precautions and recommendations. J Travel Med. 2010 Jan-Feb;17(1):32-47. Abstract Full text (in our servers)
  13. Schmidt JV, Kroger AT, Roy SL. Report from the CDC. Vaccines in women. J Womens Health (Larchmt). 2004 Abstract
  14. Bohlke K, Galil K, Jackson LA, Schmid DS, Starkovich P, Loparev VN, Seward JF. Postpartum varicella vaccination: is the vaccine virus excreted in breast milk? Obstet Gynecol. 2003 Nov;102(5 Pt 1):970-7. Abstract
  15. Pabst HF, Spady DW, Pilarski LM, Carson MM, Beeler JA, Krezolek MP. Differential modulation of the immune response by breast- or formula-feeding of infants. Acta Paediatr. 1997 Abstract

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