Last update May 21, 2021

Demanol

Limited compatibility

Unsafe. Moderate/severe adverse effects. Compatible under certain circumstances. Follow-up recommended. Use safer alternative or discontinue breastfeeding from 5 to 7 T ½ . Read Commentary.

Psychostimulant and muscarinic cholinergic agonist.
Marketed in association with other drugs in products indicated, without proof of their efficacy, to improve memory and physical and mental fatigue.
Also used in cosmetic treatments.
Oral use.

At the date of the last update, the authors did not find any published data on its excretion in breast milk.

The limited pharmacokinetic data available (low molecular weight, high pKa) make it likely that it may be transferred to breast milk in a possibly significant amount.

Product with very few bibliographic references, marketed in few countries. Considered a drug of low therapeutic utility (SEFAP 2012, INSALUD 2001).

Until more published data is known about this drug in relation to breastfeeding, known safer alternatives are preferable, especially during the neonatal period and in the event of prematurity.

In general, multiple drug combinations are not recommended, nor are drugs of unproven efficacy.

Alternatives

We do not have alternatives for Demanol.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Demanol is also known as Deanol. Here it is a list of alternative known names::


Demanol in other languages or writings:

Group

Demanol belongs to this group or family:

Tradenames

Main tradenames from several countries containing Demanol in its composition:

Pharmacokinetics

Variable Value Unit
Molecular weight 89 daltons
pKa 15.59 -
Tmax 0.5 hours
4 hours

References

  1. AEMPS. Denubil (Deanol-Heptaminol). Ficha técnica. 2019 Full text (in our servers)
  2. SEFAP. Sociedad Española de Farmacéuticos de Atención Primaria. Propuesta de medicamentos a desfinanciar por el Sistema Nacional de Salud. . 2012 Full text (in our servers)
  3. INSALUD. Área de Gestión de Farmacia. Subdirección General de Atención Primaria. Instituto Nacional de la Salud. Utilidad terapéutica de los medicamentos financiados por el Sistema Nacional de Salud. . 2001 Full text (in our servers)

Total visits

2,719

Help us improve this entry

How to cite this entry

Do you need more information or did not found what you were looking for?

   Write us at elactancia.org@gmail.com

e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America

Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM