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It is an oxazolinic corticosteroid derivative of prednisolone with mainly glucocorticoid activity equivalent to prednisolone. It is used in rheumatic, collagen, allergic and immune-based diseases. Oral administration.
At the time of last update, we found no published data on its excretion in breast milk.
Its moderately high molecular weight, its wide distribution volume and rapid elimination make it probably safe during breastfeeding, especially in non-chronic use.
It does not interfere with prolactin secretion. (Barbieri 1985)
Until more data on this drug in relation to breastfeeding are known, safer alternatives may be preferable, especially during the neonatal period and in case of prematurity.