Last update Jan. 29, 2017

Cromolyn Sodium

Compatible

Safe substance and/or breastfeeding is the best option.

It is administered by inhalation for the prevention of asthma and atopic rhinitis, orally for food allergies and topically on dermatologic and ophthalmologic conditions.

At latest update relevant published data on excretion into breast milk were not found.

There is a consensus among experts and scientific societies on considering Sodium Chromoglycate as compatible while breastfeeding (Nelson 2001, National Asthma Education 2004, Powrie 2006) because of a minimal absorption and low plasma levels appearing in the mother (AEMPS 2013, Davis 2015).

The small dose used and low plasma absorption of most inhaled preparations (either buccal or nasal), topically apply as ophthalmologic or dermatologic preparations, make it unlikely any passage in a significant amount into breastmilk.

WHO List of Essential Medicines 2002: compatible while breastfeeding.

Alternatives

We do not have alternatives for Cromolyn Sodium since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

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Other names

Cromolyn Sodium is also known as Sodium Cromoglicate.


Cromolyn Sodium in other languages or writings:

Groups

Cromolyn Sodium belongs to these groups or families:

Tradenames

Main tradenames from several countries containing Cromolyn Sodium in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. <1 oral. 7-10 inhal. 0.03 oft. %
Molecular weight 512 daltons
Protein Binding 65 %
Tmax 0.2 hours
T½ 1.3 hours

References

  1. Davis C. Cromolyn. Drug Summary. 2015 Full text (in our servers)
  2. AEMPS. Cromoglicato. Ficha técnica. 2013 Full text (in our servers)
  3. National Asthma Education and Prevention Program Asthma and Pregnancy Working Group. Managing asthma during pregnancy: recommendations for pharmacologic treatment-2004 update. 2004;1-57. None 2004 Full text (link to original source) Full text (in our servers)
  4. Nice FJ, De Eugenio D, Dimino TA, Freeny IC, Rovnack MB, Gromelski JS. Medications and Breast-Feeding: A Guide for Pharmacists, Pharmacy Technicians, and Other Healthcare Professionals. Part I. J Pharm Technol 2004;20:17-27. doi: 10.1177/875512250402000106.
  5. WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Abstract Full text (link to original source) Full text (in our servers)

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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America

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