Last update March 2, 2025

Creatine, Creatine Phosphate, Phosphocreatine

Likely Compatibility

Fairly safe. Mild or unlikely adverse effects. Compatible under certain circumstances. Follow-up recommended. Read Commentary.

Creatine is an endogenous substance, derived from amino acids, found mainly in the skeletal muscle of vertebrate animals, milk and eggs. It has been used in cardiac, metabolic, neuromuscular disorders and as a dietary supplement to improve exercise performance and muscle mass. Oral administration.

At the date of the last update we found no published data on its excretion in breast milk.

Creatine is found in breast milk at a concentration of 33 mg/L (Lawrence 2016, p767) and provides up to 10% of the infant's creatine requirement, the remainder being synthesized de novo. (Edison 2013)

No significant side effects from creatine supplementation have been published. (Antonio 2021, Poortmans 2000)

Alternatives

We do not have alternatives for Creatine, Creatine Phosphate, Phosphocreatine.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

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Other names

Creatine, Creatine Phosphate, Phosphocreatine in other languages or writings:

Groups

Creatine, Creatine Phosphate, Phosphocreatine belongs to these groups or families:

Tradenames

Main tradenames from several countries containing Creatine, Creatine Phosphate, Phosphocreatine in its composition:

References

  1. Antonio J, Candow DG, Forbes SC, Gualano B, Jagim AR, Kreider RB, Rawson ES, Smith-Ryan AE, VanDusseldorp TA, Willoughby DS, Ziegenfuss TN. Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show? J Int Soc Sports Nutr. 2021 Feb 8;18(1):13. Abstract Full text (link to original source)
  2. Lawrence RA, Lawrence RM. Breastfeeding. A guide for the medical profession. Eighth Edition. Philadelphia: Elsevier; 2016
  3. Edison EE, Brosnan ME, Aziz K, Brosnan JT. Creatine and guanidinoacetate content of human milk and infant formulas: implications for creatine deficiency syndromes and amino acid metabolism. Br J Nutr. 2013 Sep 28;110(6):1075-8. Abstract Full text (link to original source)
  4. Poortmans JR, Francaux M. Adverse effects of creatine supplementation: fact or fiction? Sports Med. 2000 Sep;30(3):155-70. Review. Abstract

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