Last update March 12, 2022
Very Low Risk
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Chloroquine is also known as
Chloroquine in other languages or writings:
Chloroquine belongs to this group or family:
|Oral Bioavail.||52 - 100||%|
|Molecular weight||320 - 516||daltons|
|Protein Binding||55 (46 - 74)||%|
|VD||200 - 800||l/Kg|
|Tmax||2.7 - 6.9||hours|
|T½||72 - 291||hours|
|Theoretical Dose||0.18 (0.03 - 0.42)||mg/Kg/d|
|Relative Dose||2.6 (0.4 - 6.0)||%|
|Ped.Relat.Dose||2.1 (0.36 - 5.1)||%|
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e-lactancia is a resource recommended by Asociación Pro Lactancia Materna (APROLAM) of Mexico
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Derived from aminoquinolone. Indicated in the treatment of malaria, hepatic amebiasis, HIV, rheumatoid arthritis, systemic lupus erythematosus and sarcoidosis, among other pathologies. Oral or intravenous administration.
It is excreted in human milk in a clinically non-significant amount. (Law 2008, Edstein 1986, Deturmeny 1984)
No problems have been observed in infants whose mothers took it. (Chen 2010)
It is an authorized medication for infants from 4 weeks of age (BNF 2018). Since mefloquine can be safely prescribed to young infants, exposure to the small amount excreted in the mothers’ milk is also safe. (CDC 2019)
Avoid in glucose-6-phosphate-dehydrogenase deficiency. Monitor for jaundice during the neonatal period and in the event of prematurity.
Various medical societies, expert authors, and expert consensus consider the use of this medication safe during breastfeeding(Hale, CDC 2019, Saito 2018, Lalloo 2016, Lawrence 2016 p464 and 784, Götestam 2016, Levy 2016, Briggs 2015, Schaefer 2015, WHO 2010, Zrour 2010, Chen 2010, Law 2008, Østensen 2006, Fulton 1992)
WHO List of Essential Medicines: compatible with breastfeeding. (WHO 2002)
American Academy of Pediatrics: medication usually compatible with breastfeeding. (AAP 2001)