Last update Nov. 2, 2023

Carbocisteine

Very Low Risk

Safe. Compatible. Minimal risk for breastfeeding and infant.

Carbocisteine is an expectorant mucolytic used to alleviate respiratory diseases associated with increased mucus viscosity. Oral administration three times a day.

At the time of the last update, we found no published data on its excretion in breast milk.

Its high volume of distribution makes it unlikely to pass into breast milk in significant concentration.

The absorption from ingested mother's milk to the infant's plasma is hampered by a low oral bioavailability (Irish 2014, AEMPS 1998), with this being a reason for a nil or minimal plasma level in the infant, except in prematures or soon after birth when absorption would be higher. 

It is a product that has only mild or few side-effects when used at normal dose. The manufacturer considers it probably compatible with lactation. (CINFA 2021)

Alternatives

We do not have alternatives for Carbocisteine since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Carbocisteine is also known as


Carbocisteine in other languages or writings:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 10 %
Molecular weight 179 daltons
VD 0.9 l/Kg
pKa 1.84 -
Tmax 1 - 1.7 hours
1.33 - 3.1 hours

References

  1. CINFA. Carbocisteina. Ficha técnica. 2021 Full text (in our servers)
  2. Irish Medicines Board. Carbocisteine. Drug Summary. 2014 Full text (in our servers)
  3. AEMPS. Carbocisteína. Ficha técnica. 1998 Full text (in our servers)

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