Last update Oct. 30, 2023

Carbarsona

High Risk

Poorly safe. Evaluate carefully. Use safer alternative or interrupt breastfeeding 3 to 7 T ½ (elimination half-lives). Read the Comment.

Carbarsone is an organic derivative of pentavalent arsenic that was used as an antiprotozoal drug to treat intestinal amebiasis (Chopra 1933). Today it is for veterinary use only in most countries.

At the time of the last update, we found no published data on its excretion in breast milk.

Product with very few bibliographic references and/or very old, marketed in few countries. The absence of known pharmacokinetic data does not allow predicting its possible excretion in breast milk.

Alternatives

  • Metronidazole ( Safe. Compatible. Minimal risk for breastfeeding and infant.)
  • Tinidazole ( Safe. Compatible. Minimal risk for breastfeeding and infant.)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Carbarsona is also known as


Carbarsona in other languages or writings:

Group

Carbarsona belongs to this group or family:

Tradenames

Main tradenames from several countries containing Carbarsona in its composition:

Pharmacokinetics

Variable Value Unit
Molecular weight 260 daltons
pKa 3.5 -

References

  1. Nagata N, Marriott D, Harkness J, Ellis JT, Stark D. Current treatment options for Dientamoeba fragilis infections. Int J Parasitol Drugs Drug Resist. 2012 Sep 3;2:204-15. Abstract Full text (link to original source)
  2. Chopra RN, Sen B, Sen S. Treatment of Chronic Intestinal Amœbiasis with Carbarsone. Ind Med Gaz. 1933 Jun;68(6):315-319. No abstract available. Abstract Full text (link to original source)

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