Cadexomer Iodine

Iodine is used as a topical antiseptic for the treatment and prevention of infections (bacteria, fungi, viruses, protozoa, cysts and spores) in wounds and for preoperative preparation of skin and mucous membranes. Iodine is used as such in alcoholic or aqueous solution (Lugol's solution) at 2% or 2.5%. The use of iodine as a disinfectant is preferred in the form of iodophors, compounds that release iodine slowly, such as Povidone iodine or iodinated Cadexomer. Topical application on skin, mouth and vagina.

Elevation of iodine levels in plasma and breast milk, altered neonatal hypothyroidism screening tests and transient hypothyroidism have been demonstrated in infants of mothers exposed to topical treatment with iodinated disinfectant. ^{(Kurtoğlu 2009, Smith 2006, Casteels 2000, Koga 1995, Arena 1989, Rakover 1989, Chanoine 1988 &1988, Delange 1988, Danziger 1987)}

Avoid use in delivery areas, operating theatres (caesarean sections), neonatal and infant units and throughout lactation. ^{(WHO 2002, Chanoine 1988)}. During breastfeeding, it is not advisable to use mouthwashes or vaginal irrigations with iodinated products.

If there has been a large exposure to iodine, some authors advise that the mother express and discard milk for one week after discontinuing iodine therapy ^{(Smith 2006)}. If possible, do an analysis of iodine in plasma and breast milk to guide the action.

Occasional application on small wounds, especially on healthy skin, is not dangerous and does not require any analysis in the infant.

See below the information of this related product:

• Povidone-Iodine (Unsafe. Moderate/severe adverse effects. Compatible under certain circumstances. Follow-up recommended. Use safer alternative or discontinue breastfeeding from 5 to 7 T ½ . Read Commentary.)