Last update Dec. 20, 2022
Very Low Risk
Antiviral very active against Herpes simplex and Herpes zoster-varicella. Intravenous, oral and topical (dermatological and ophthalmological) administration. Its use is authorized in newborns and infants.
Despite its higher concentration in breast milk than in plasma (Mactal 2001,Bork 2000, Lau 1987), it is excreted in breast milk in a clinically insignificant amount (Drake 2012, Bork 1995, Taddio 1994, Don 1991, Meyer 1988, Lau 1987), much lower than the dose used in newborns and infants (Sheffield 2002), and no problems have been observed in infants whose mothers took it. (Agarwal 2019, Taddio 1994)
Systemic absorption of topical cutaneous acyclovir is negligible. (Mactal 2001)
List of WHO essential medicines: compatible with breastfeeding (WHO / UNICEF 2002). American Academy of Pediatrics: medication usually compatible with breastfeeding. (AAP 2001)
We do not have alternatives for C8H11N5O3 since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.
Thank you for helping to protect and promote breastfeeding.
e-lactancia is a resource recommended by Asociación Pro Lactancia Materna (APROLAM) of Mexico
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM