Last update May 10, 2021
Likely Compatibility
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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C26 H26 ClN3 is Rupatadine Fumarate in Molecular formula.
Is written in other languages:Main tradenames from several countries containing C26 H26 ClN3 in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 45 | % |
Molecular weight | 532 | daltons |
Protein Binding | 99 | % |
VD | 138 | l/Kg |
Tmax | 0.75 | hours |
T½ | 5.9 | hours |
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e-lactancia is a resource recommended by El Parto Es Nuestro of Spain
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Second generation antihistamine and piperidine-type compound, without the sedative and anticholinergic effects of first generation antihistaminics.
Pharmacokinetic data (moderately high molecular weight, very large volume of distribution and high percentage of protein binding) make it unlikely an excretion into breast milk in significant amounts.
Expert authors consider antihistamines compatible with breastfeeding (So 2010).
Until more published data on this drug regarding breastfeeding is available, safer alternatives of better known drugs should be preferable, especially during the neonatal period and in case of prematurity.
Follow-up the baby for drowsiness and inappropriate infant feeding.