Last update Jan. 11, 2023
Very Low Risk
It is a natural bile acid present in human bile. It suppresses the hepatic synthesis and secretion of cholesterol and inhibits the intestinal absorption of cholesterol. It is an epimer of chenodeoxycholic acid. It is used for the treatment of primary biliary cirrhosis, the dissolution of gallstones, and the treatment of hepatobiliary disorders associated with cystic fibrosis in pediatric patients. Oral administration one to three times a day.
It is excreted in breast milk in a clinically insignificant or undetectable amount (Šimják 2022, Vítek 2010, Brites 1998, Rudi 1996), with no side-effects being observed among infants of treated mothers. (Šimják 2022, Erol 2018, Efe 2014, Vítek 2010, Goh 2001, Brites 1998, Rudi 1996)
Iy is a bile salt that appears in low amount in the serum because it is absorbed to the portal circulation and completely excreted into biliary duct.
Bile salts are found in breast milk in small amounts (Forsyth 1983). Altered bile acid ratios in breast milk have been linked to prolonged jaundice from breastfeeding. (Forsyth 1990)
It is a medication that has been used for treatment of newborns and infants.
Expert authors consider the use of this medication possible during breastfeeding. (de Vries 2019, Mahadevan 2006)
We do not have alternatives for C24H40O4 since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2012 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM