Last update June 17, 2017

C24H20Cl2N2OS

Very Low Risk

Safe. Compatible. Minimal risk for breastfeeding and infant.

A topical anti-fungal treatment from the imidazole family applied to the skin or vaginally.

Negligible systemic absorption through the skin (Effik 2010) or vaginal mucosa (Novelli 1991) make it very unlikely that significant amounts pass into breast milk.

Do not apply on nipple-areola or alternatively clean before breastfeeding.

It is advisable to avoid the application to the nipple of creams, gels and other topical products containing paraffin (mineral oil) so that the infant does not absorb them (Concin 2008, Noti 2003)

Alternatives

We do not have alternatives for C24H20Cl2N2OS since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

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Other names

C24H20Cl2N2OS is Fenticonazole Nitrate in Molecular formula.

Is written in other languages:

C24H20Cl2N2OS is also known as

Groups

C24H20Cl2N2OS belongs to these groups or families:

Tradenames

Main tradenames from several countries containing C24H20Cl2N2OS in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. Der: 0. Vag: 1 %
Molecular weight 518 daltons

References

  1. Effik. Fenticonazol crema. Ficha técnica. 2010 Full text (in our servers)
  2. Concin N, Hofstetter G, Plattner B, Tomovski C, Fiselier K, Gerritzen K, Fessler S, Windbichler G, Zeimet A, Ulmer H, Siegl H, Rieger K, Concin H, Grob K. Mineral oil paraffins in human body fat and milk. Food Chem Toxicol. 2008 Abstract
  3. Noti A, Grob K, Biedermann M, Deiss U, Brüschweiler BJ. Exposure of babies to C15-C45 mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol. 2003 Abstract
  4. Novelli A, Periti E, Massi GB, Masi R, Mazzei T, Periti P. Systemic absorption of 3H-fenticonazole after vaginal administration of 1 gram in patients. J Chemother. 1991 Abstract

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