Last update Nov. 5, 2024
Compatible
We do not have alternatives for C23H14Na2O11 since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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C23H14Na2O11 is Sodium Cromoglicate, Cromolyn Sodium in Molecular formula.
Is written in other languages:C23H14Na2O11 is also known as
C23H14Na2O11 belongs to these groups or families:
Main tradenames from several countries containing C23H14Na2O11 in its composition:
| Variable | Value | Unit |
|---|---|---|
| Oral Bioavail. | <1 oral. 7-10 inhal. 0.03 oft. | % |
| Molecular weight | 512 | daltons |
| Protein Binding | 65 | % |
| pKa | 1.61 | - |
| Tmax | 0.2 | hours |
| T½ | 1.3 - 1.5 | hours |
Write us at elactancia.org@gmail.com
e-lactancia is a resource recommended by Instituto de Salud Infantil, Grecia-Institute of Child´s Health in Greece
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
It is a chromogenic complex that acts by inhibiting the release of chemical mediators from sensitized mast cells. It is administered by inhalation for the prevention of asthma and atopic rhinitis, orally in food allergies and topically in dermatology and ophthalmology.
At the date of last update we found no published data on its excretion in breast milk.
The small dose and low plasma absorption of most inhaled (buccal or nasal), ophthalmologic or topical dermatologic preparations make the passage of significant amounts into breast milk unlikely.
Their low oral bioavailability makes it difficult for them to pass into infant plasma from ingested breast milk, except in premature infants and the immediate neonatal period in which there may be greater intestinal permeability.
There is consensus among experts and scientific societies that sodium cromoglycate is compatible with breastfeeding(Hale, LactMed, Brigggs 2015, Nelson 2001, National Asthma Education 2004, Powrie 2006, Nice 2004) due to its minimal absorption and low plasma levels in the mother. (AEMPS 2013, Davis 2015)
WHO 2002 essential drug list: compatible with breastfeeding. (WHO 2002)