Last update Sept. 4, 2017

C17H21NO3

Likely Compatibility

Fairly safe. Mild or unlikely adverse effects. Compatible under certain circumstances. Follow-up recommended. Read Commentary.

Since the last update we have not found published data on its excretion in breast milk.

Its high percentage of plasma protein binding make it very unlikely that significant amounts will pass into breast milk.

Until there is more published data on this drug in relation to breastfeeding, safer known alternatives may be preferable, especially during the neonatal period and in case of prematurity.

Alternatives

  • Diclofenac (Safe substance and/or breastfeeding is the best option.)
  • Ibuprofen (Safe substance and/or breastfeeding is the best option.)
  • Paracetamol (Safe substance and/or breastfeeding is the best option.)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

C17H21NO3 is Etodolac in Molecular formula.

Is written in other languages:

C17H21NO3 is also known as

Tradenames

Main tradenames from several countries containing C17H21NO3 in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 80 - 100 %
Molecular weight 287 daltons
Protein Binding 95 - 99 %
VD 0.4 l/Kg
pKa 4.7 -
Tmax 1 - 2 hours
7.3 hours

References

  1. AA Pharma. Etodolac. Drug Summary. 2010 Full text (in our servers)

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