Last update May 1, 2016

C16H13Cl2NO4

Very Low Risk

Safe. Compatible. Minimal risk for breastfeeding and infant.

Antiinflammatory drug that is similar to diclofenac and used in the treatment of rheumatoid arthritis, ankylosing spondylitis and osteoartrirts.

At latest update no published data on excretion into breast milk were found.

Its high plasma protein-binding capacity makes the passage into milk be unlikely.

Diclofenac which is part of the same family of antiinflammatory drugs is excreted in non-significant amount into breast milk.

Alternatives

  • Diclofenac ( Safe. Compatible. Minimal risk for breastfeeding and infant.)
  • Ibuprofen ( Safe. Compatible. Minimal risk for breastfeeding and infant.)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

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Other names

C16H13Cl2NO4 is Aceclofenac in Molecular formula.

Is written in other languages:

Group

C16H13Cl2NO4 belongs to this group or family:

Tradenames

Main tradenames from several countries containing C16H13Cl2NO4 in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 100 %
Molecular weight 354 daltons
Protein Binding > 99 %
Tmax 1 - 3 hours
T½ 4 hours

References

  1. Hutchinson S, Marmura MJ, Calhoun A, Lucas S, Silberstein S, Peterlin BL. Use of common migraine treatments in breast-feeding women: a summary of recommendations. Headache. 2013 Abstract Full text (link to original source) Full text (in our servers)
  2. Aceclofenac Data Sheet 2009 Full text (in our servers)
  3. Aceclofenaco Ficha técnica 2007 Full text (in our servers)
  4. Hirose M, Hara Y, Hosokawa T, Tanaka Y. The effect of postoperative analgesia with continuous epidural bupivacaine after cesarean section on the amount of breast feeding and infant weight gain. Anesth Analg. 1996 Abstract

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