Last update May 4, 2020

C11 H15 NO5

Likely Compatibility

Fairly safe. Mild or unlikely adverse effects. Compatible under certain circumstances. Follow-up recommended. Read Commentary.

Is a centrally acting skeletal muscle relaxant with depressant effect on the central nervous system.
Oral administration 4 times a day.

At latest update no relevant data on this subject were found in connection with breastfeeding.

Despite excretion into breast milk is likely, the elimination rate is quite rapid.

Whenever possible use a minimal dose and let it to pass two hours until the next feed.
Watch for occurrence of symptoms like sedation and feeding refusal in the infant.
Avoid in infants younger than one month of age.

Alternatives

We do not have alternatives for C11 H15 NO5.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

C11 H15 NO5 is Methocarbamol in Molecular formula.

Is written in other languages:

C11 H15 NO5 is also known as

Group

C11 H15 NO5 belongs to this group or family:

Tradenames

Main tradenames from several countries containing C11 H15 NO5 in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 100 %
Molecular weight 241 daltons
Protein Binding 46 - 50 %
VD 0.48 l/Kg
pKa 13.6 -
Tmax 1.1 hours
1.2 hours

References

  1. AEMPS - FAES F. Metocarbamol (Robasen). Ficha técnica. 2015 Full text (in our servers)
  2. PDR.net. Methocarbamol. Drug Summary. 2014 Full text (in our servers)
  3. Forist AA, Judy RW. Comparative pharmacokinetics of chlorphenesin carbamate and methocarbamol in man. J Pharm Sci. 1971 Nov;60(11):1686-8. No abstract available. Abstract

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